they certainly dont use a certain spot, my poo all over the place. With young ones it is very small and hard to spot unless its on the glass then you cant miss it. Depending on your set up type washing it away with misting isnt neccesarily bad. Cleaning the enclosure at least once a week with a sinlge juvie should be fine, just make sure you take out the decorations and wash them off. If you have a sprayer on your sink that works great.