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T+ and T- Black Rats, Homozygous for Both?


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Posted by RobG on March 19, 2003 at 02:34:50:

I was having a discussion with someone that breeds Ball Pythons the other day about T+ and T- animals. I was telling them that it is possible for an animal to be genetically homozygous for both traits. There are T+ and T- Black Rats. Does anyone have a Black Rat that is homozyous for both? I am thinking that someone does. My thinking is that since the metabolic pathways that are affected are different they can be homozyougs for both traits, I think I've read that they are totally different genes. One causes no tyrosinase production which leads to a usually white and yellow animal T-. While the other prevents the formation of black melamine from other intermediates in the melamine formation process, which leads to a Lavendar looking animal, the T+. Because of this a Doulbe Homozygous T+ and T- animal would look like a T- animal. This should be because there is no tyrosinase, it wouldn't matter what the T+ gene affects because there is no tyrosinase to create the "metabolite" which later on in the melamine formation cascade causes the typical darker T+ albino colors. Any clarification of my ideas/thoughts/knowlege and input would be appreciated.

In other words I'm say:
You can have a doulbe Homozygous T+ and T- animal
But it would look like a T- due to the facts that I stated above

Thanks,

Robert Gonzalez



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