We've never had that problem but when I first joined this forum I went back and read a lot of the previous post and it seems like several others had that same problem. They ahd a mail who usually had "tame"breeding seasons with just maybe a slight bit more agitation than usual and then suddenly they turned into devil iguana!! From what I read most did tame back down after breeding season finished but there were a few who stayed more wild from then on. I don't know if there was some other change at the same time like less human contact or more of a show of fear towards the iguana.
The only suggestion I have though is try not to show your scared of it but keep a very close eye on it!!