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Posted by jeremy on February 02, 2002 at 20:58:45:
In Reply to: that is a total lie! posted by dave f on February 02, 2002 at 14:06:44:
: in chameleons, i can definitely dispute just about all of that.
: first, by using recommended dosages, i was able to successfully kill off a few WC chameleons with flagyl.
: second, i was successful at frying several chameleon nervous systems with flagyl, and contrary to the post below, they symptoms never passed on. well, they did, but only when the animal eventually died (this happened to 3 CB chams. they lived only about 2 more years!).
: it is disturbing, how free wheeling people are with medications.
: a question i like to ask people who pop down aspirin or other NSAIDS for pain is: "what do you think causes your headaches (or other ailment)? do you really believe it's an aspirin deficiency?"
: the day i hear a good answer to that is the day heck freezes over.
:
: : This was sent to me from a vet student friend who checked up on the issue. Just more things to think about.
: : "...not only Flagyl toxicity is rare, but there are characteristic signs of it. You'll ALWAYS see neurological signs- the toxicity that results is because of it crossing the blood-brain barrier at high enough concentrations to activate certain regions, especially those involving balance and coordination. Thus, you'll see ataxia, wandering around, loss of coordination, twirling, star-gazing and the like. It has been reported that there can be GI signs, but you'll only see it with the neurological cases. Both dogs and humans have reported overdose signs, but within 12 hours of discontinuance of the drug, all side effects abated. In no animals studied of any species, metronidazole has caused liver of kidney damage, blood dyscrasias, or any permanent effects (this includes species/individuals that are known to be more sensitive to metronidazole). Oh, one more thing, it's also been shown several times over to have poor oral absorbtion. Most of the drug just passes through the GI tract, thus being a great compound for treating enteritis"
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