:3. Supplement your babys and pregnant females twice weekly and adult males and non-pregnant females once weekly. Use a mixture of half minerall half reptivite or any other brands just make sure your mixture is half minerals and half vitamins. I have NEVER ran into vitamin or mineral toxicity just problems with deficincy like non movement of limbs and soft bones. I raised one litter of babies with supplement and one without. The ones with supplement grew much faster.