A lot will depend on the quality of the mouse, its freshness, etc. If it has sat out for more than an hour or two, I woudn't reuse it. In fact, I never re-freeze an uneaten mouse/rodent. That is why I keep a few resident "garbage disposals" at our facility: alligator snapping turtle, common snapper, american alligator....nothing gets wasted around here!
:If my snake will not eat a thawed mouse can\should I re-freeze it? Please advise thanxs Dave